By Morton Lippmann Ph.D. (auth.), J. C. M. Marijnissen, L. Gradoń (eds.)
A team of hugely esteemed aerosol scientists - physicists, chemists, biologists and toxicologists - met in Warsaw in September, 1995, as a way to speak about the newest advancements within the box of aerosol wellbeing and fitness topics, together with inhalation, lung delivery and deposition. the connection of those topics with the surroundings was once additionally addressed.
This publication comprises the court cases of the Workshop and likewise files the resultant panel discussions.
topic Index included.
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Additional info for Aerosol Inhalation: Recent Research Frontiers: Proceedings of the International Workshop on Aerosol Inhalation, Lung Transport, Deposition and the Relation to the Environment: Recent Research Frontiers, Warsaw, Poland, September 14–16, 1995
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Since 1991, IARC has explicitly made provision for the use of mechanistic data in the classification process (IARC, 1992). Mechanistic data can be used to upgrade the classification of a chemical. For example, ethylene oxide was reclassified to Group 1 (a human carcinogen) from Group 2a (a probable human carcinogen) based on mechanistic considerations (IARC, 1994). Presumably a chemical might be placed in a lower category than would otherwise be the case based on mechanistic data. An example of such a situation, which draws on experience in the United States, is the review of chemicals shown to produce kidney tumors in male rats via a mechanism involving a male rat-specific protein, cx2u-globulin.
Group 4. The agent (mixture) is classifiable as to its carcinogenicity. (a) Inadequate. Group 3. The agent (mixture or carcinogenic to humans. evidence from other relevant data. Limited together with supporting (c) Inadequate. The exposure circumstance entails exposures that are possibly Sufficient. (b) Inadequate. possibly carcinogenic to humans. Less than sufficient. (a) Limited. Group 2b. The agent (mixture) is Table 3. (continued) pharmacokinetics, physicochemical parameters, and analogous biological agents.
Aerosol Inhalation: Recent Research Frontiers: Proceedings of the International Workshop on Aerosol Inhalation, Lung Transport, Deposition and the Relation to the Environment: Recent Research Frontiers, Warsaw, Poland, September 14–16, 1995 by Morton Lippmann Ph.D. (auth.), J. C. M. Marijnissen, L. Gradoń (eds.)